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Cell 163 (6), 14841499

Therefore, by activating this NCOA4-mediated ferritinophagy pathway, Erastin promotes the release of free iron, which in turn amplifies ROS production and lipid peroxidation, resulting in an autophagy-dependent mode of ferroptosis

IL-15, which is involved in the activation and maturation of anti-tumour T cells, including natural killer (NK) cells and CD8+ T cells (76), was demonstrated to be significantly increased following metformin treatment